Example 1 · difficulty 4/5
When adrenaline binds to its receptor on a liver cell membrane, which sequence correctly represents the signal transduction events that follow?
- A. Adenyl cyclase is activated first, after which the G-protein couples the receptor to the enzyme
- B. Adrenaline diffuses into the nucleus and directly switches on the genes coding for glycogen-splitting enzymes
- C. The receptor itself converts ATP to cyclic AMP without any G-protein participation
- D. Hormone–receptor binding activates the G-protein, which turns on adenyl cyclase; ATP is converted to cAMP, and cAMP activates protein kinases that trigger glycogen breakdown